Mitigating antimicrobial resistance: Implications for ecological and public health

Antimicrobial resistance is a global problem which affects both developing and developed nations. However, the mandate for international measure enforcements are limited. Significant number of bacteria species are developing increased resistance to antibiotic. This makes some infections difficult, sometimes impossible to treat due to trends in multiple antibiotic resistance profile of the bacteria isolates. Hence, treatment regimens may entail an important health risk in the future. The problem of antibiotic resistance is largely invisible which makes it a global threat to public health. Antibiotic-resistance have no respect for international borders. This makes international cooperation a priority when considering antibiotic resistance. A significant amount of work remains undone so as to mitigate this threat in the Africa regions and the world economy. The approach to antibiotic resistance that is proposed in this project will address nexus where human health is threatened by antibiotic resistance bacteria such as animals, healthcare, food, environment and water. It will include an
integrated One Health approach based on a public health perspective. Specific measures will be undertaken in each nexus. Particular attention is required for international activities and innovation.
This project will bridge the knowledge gap between the mechanisms by which socio-economic and ecological factors impact the fate of antibiotic resistance.